Can you mix alcohol and Benadryl? No. If you are using Benadryl to help with allergies it is recommended to avoid alcohol until you know the body's response to the medication. However, mixing any of the drugs (prescribed or not) with alcohol can have unpredictable and unwanted negative effects.

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Mixing Benadryl And Alcohol Dangerous Effects & Treatment
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Mixing Benadryl And Alcohol Dangerous Effects & Treatment

It is not recommended to mix (diphenhydramine) Benadryl and alcohol. Both of these substances can cause drowsiness and impair your ability to...